BDBM116958 US8637532, 685

SMILES NC(=O)c1cccc2c(NCC3CC=CC(=NC(O)c4ccn[nH]4)C3)ncnc12

InChI Key InChIKey=WHOKGFKDKLABFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 116958   

TargetAurora kinase A(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116958BDBM116958(US8637532, 685)
Affinity DataIC50: 2.80nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent

TargetAurora kinase B(Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 116958BDBM116958(US8637532, 685)
Affinity DataIC50: 5nMAssay Description:The Aurora assays described here are performed on two Caliper Life Sciences systems: the LC3000 and the Desktop Profiler. These provide data on enzym...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
US Patent