BDBM11703 (2S)-Cyanopyrrolidine analogue 18g::1-{4-[3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)propanoyl]piperazin-1-yl}-1,6-dihydropyridine-3-carbonitrile

SMILES O=C(CNCCC(=O)N1CCN(CC1)N1CC=CC(=C1)C#N)N1CCC[C@H]1C#N

InChI Key InChIKey=GUSVKVKGPJDNCE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 11703   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11703(1-{4-[3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoeth...)
Affinity DataIC50: 629nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11703(1-{4-[3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoeth...)
Affinity DataIC50: 2.00E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM11703(1-{4-[3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoeth...)
Affinity DataIC50: 1.81E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed