BDBM11710 (2S)-Cyanopyrrolidine analogue 18n::3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-N-(2-phenylpropan-2-yl)propanamide::3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino]-N-(1-methyl-1-phenylethyl)propionamide::CHEMBL201158

SMILES CC(C)(NC(=O)CCNCC(=O)N1CCC[C@H]1C#N)c1ccccc1

InChI Key InChIKey=XUDJEDOIMGXNTK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11710   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 119nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 119nMAssay Description:In vitro inhibition of DPP-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 8.34E+3nMAssay Description:In vitro inhibition of DPP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 8.34E+3nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of DPP-IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 2.00E+4nMAssay Description:In vitro inhibition of FAP, sepraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11710(CHEMBL201158 | 3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed