BDBM11712 (2S)-Cyanopyrrolidine analogue 18p::3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-N-phenylpropanamide::3-[2-(2-Cyano-(S)-pyrrolidin-1-yl)-2-oxoethylamino]-N-phenylpropionamide::CHEMBL371480

SMILES O=C(CCNCC(=O)N1CCC[C@H]1C#N)Nc1ccccc1

InChI Key InChIKey=XNUKFQAGOWQDET-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 11712   

TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11712(3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: 298nMAssay Description:In vitro inhibition of DPP-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11712(3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: 298nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11712(3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: 855nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM11712(3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: 856nMAssay Description:In vitro inhibition of DPP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11712(3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: 5.72E+3nMAssay Description:In vitro inhibition of DPP-IIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM11712(3-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}ami...)
Affinity DataIC50: 5.72E+4nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2006
Entry Details Article
PubMed