BDBM117146 US8648092, 77

SMILES CCCCN(CC)Cc1c(CCCC)nc2cc(\C=C\C(=O)NO)ccn12

InChI Key InChIKey=YIPFUXZLQYMKCV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 117146   

TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117146(US8648092, 77)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of recombinant human GST-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells Fluor-de-lys as substrate measured after 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Indian Csir-Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM117146(US8648092, 77)
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
US Patent