BDBM118846 US8674113, 103

SMILES CN(CC#C)c1cc2n(C)c(Nc3c(Cl)ccc(CNC(=O)C(C)(C)C)c3Cl)nc2cc1C(=O)N[C@H]1CC[C@@H](CC1)C(F)(F)F

InChI Key InChIKey=OTDGBUPILJBZSW-MXVIHJGJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118846   

TargetProstaglandin E synthase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM118846(US8674113, 103)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The aim of this assay is to determine the affinity of a test compound for the mPGES-1 enzyme. 47 μl of recombinant human mPGES-1 (0.5 μg p...More data for this Ligand-Target Pair
In DepthDetails US Patent