BDBM119041 CHEMBL3086172::US8674100, 54::US9221797, 54

SMILES CC1(C)CCC(=CC1)c1cc(CC(=O)NCCCO)ccc1NC(=O)c1ncc([nH]1)C#N

InChI Key InChIKey=YXGAVVOMJBANIK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 119041   

TargetMacrophage colony-stimulating factor 1 receptor [555-568](Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)
Affinity DataIC50: 2.40nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2016
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)
Affinity DataIC50: 2.40nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2014
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)
Affinity DataIC50: 100nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed