BDBM11914 (1S,3S,5S)-2-[(2S)-pyrrolidin-2-ylcarbonyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile::substituted diprolyl nitrile 7

SMILES O=C([C@@H]1CCCN1)N1[C@H]2C[C@H]2C[C@H]1C#N

InChI Key InChIKey=IIVGMDFYTPCILV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11914   

TargetDipeptidyl peptidase 4(Pig)
Bristol-Myers Squibb Pharmaceutical Research Institute

LigandPNGBDBM11914((1S,3S,5S)-2-[(2S)-pyrrolidin-2-ylcarbonyl]-2-azab...)
Affinity DataKi:  305nM ΔG°:  -8.79kcal/molepH: 7.4 T: 2°CAssay Description:Inhibition of human DPP-IV activity was measured under steady-state conditions by following the absorbance increase at 405 nm upon the substrate clea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2006
Entry Details Article
PubMed