BDBM119724 US8680132, MI- 791

SMILES O=C(NC1CCC(O)CC1)[C@@H]1N[C@H](CC2CCCC2)[C@]2(CNc3cc(Cl)ccc32)[C@H]1c1cccc(Cl)c1F

InChI Key InChIKey=MIXMBJVFBHEWEI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119724   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 119724BDBM119724(US8680132, MI- 791)
Affinity DataIC50: 3.00E+3nMpH: 7.5Assay Description:The binding affinity of the MDM2 inhibitors was determined using an optimized, sensitive and quantitative fluorescence polarization-based (FP-based) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2014
Entry Details
US Patent