BDBM119825 US8691852, 50

SMILES OC(=O)c1cc(cnc1Nc1c(F)cc(cc1F)-c1cccc(OC2CC2)c1)C1CC1

InChI Key InChIKey=IBMBXRGWZNBNSI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119825   

LigandPNGBDBM119825(US8691852, 50)
Affinity DataIC50: 6nMpH: 8.0Assay Description:DHODH activity and its inhibition were studied using a chromogen reduction assay with DCIP (2,6-dichlorophenol-indophenol). The substrate oxidation (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
US Patent

LigandPNGBDBM119825(US8691852, 50)
Affinity DataIC50: 6nMAssay Description:Inhibition of Homo sapiens (human) dehydroorotate dihydrogenase using 2,6-dichlorophenol-indophenol as substrate after 10 min by spectrophotometric a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article