BDBM120136 US8697708, 56

SMILES Cc1cc(Nc2nccc3nc(sc23)-c2ccccc2Cl)nc(C)n1

InChI Key InChIKey=GRYIJVOHSRGZOX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120136   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM120136(US8697708, 56)
Affinity DataKi:  8.60nM ΔG°:  -10.9kcal/molepH: 7.2 T: 2°CAssay Description:To determine the inhibition constants (Ki) of Examples 1-240, compounds were diluted serially in DMSO and added to 50 μL kinase reactions contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2014
Entry Details
US Patent