BDBM120380 US8703785, 34

SMILES CN1C(=O)CC(C)(N=C1N)c1cccc(NC(=O)c2cnc(Cl)cn2)c1

InChI Key InChIKey=WHPXSUXTRBXIHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120380   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM120380(US8703785, 34)
Affinity DataIC50: 37nMpH: 7.0 T: 2°CAssay Description:First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent