BDBM120384 US8703785, 481

SMILES Nc1ncccc1NCc1cccc(NC(=O)c2cnc(OCC#C)cn2)c1

InChI Key InChIKey=GDAPCOAWIWVVSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120384   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM120384(US8703785, 481)
Affinity DataIC50: 180nMpH: 7.0 T: 2°CAssay Description:First, 48.5 μl portions of a solution of substrate peptide (Biotin-XSEVNLDAEFRHDSGC-Eu: X=ε-amino-n-capronic acid, Eu=Europium cryptate) we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent