BDBM120389 US8703771, 2

SMILES Cc1ccc(NC(=O)c2ccc3C(CCc3c2)N2CCN(CC2)C(=O)OC(C)(C)C)cc1Nc1nccc(n1)-c1cccnc1

InChI Key InChIKey=PDJFRJFTKGLDDM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 120389   

TargetPlatelet-derived growth factor receptor beta(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120389(US8703771, 2)
Affinity DataIC50: 233nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetMast/stem cell growth factor receptor Kit(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120389(US8703771, 2)
Affinity DataIC50: 1.19E+3nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase ABL1(Human)
Harbin Gloria Pharmaceuticals

US Patent
LigandPNGBDBM120389(US8703771, 2)
Affinity DataIC50: 2.04E+3nMpH: 7.5 T: 2°CAssay Description:The activity of the compounds of this invention on Abl, c-Kit and PDGFR kinases was tested by Mobility Shift Assay (MSA). Kinase buffer: 62.5 mM HEPE...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent