BDBM120510 US8703768, 110
SMILES CC(C)(O)CNC(=O)c1cc(F)c(F)cc1NC(=O)c1nc(cnc1Nc1cncnc1)C1CC1
InChI Key InChIKey=DBBBEJWOHAQIQO-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 120510
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 0.600nMAssay Description:PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...More data for this Ligand-Target Pair
