BDBM120742 US8703767, 2

SMILES CN1CCN(CC1)c1ccc(Nc2nc(-c3cccc(NC(=O)C=C)c3)c3c[nH]nc3n2)cc1

InChI Key InChIKey=KYZNLJKIEFSDJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 120742   

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120742(US8703767, 2)
Affinity DataIC50: 187nMT: 2°CAssay Description:The primary assay for compound inhibitory activity was the ADP generation assay described herein. Test compounds were diluted to desired concentratio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
University of Utah

US Patent
LigandPNGBDBM120742(US8703767, 2)
Affinity DataIC50: 562nMT: 2°CAssay Description:Activity of compounds was routinely confirmed using a secondary assay as described herein. The secondary assay was a time resolved-FRET kinase assay....More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2014
Entry Details
US Patent