BDBM120962 US8716285, 19

SMILES ONC(=O)c1ccc2CCC(Cc2c1)Nc1nccc(n1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=HFIVCMJWKICFLR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120962   

TargetHistone deacetylase 8(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM120962(US8716285, 19)
Affinity DataIC50: 1.69E+3nMAssay Description:Compounds were tested for their ability to inhibit histone deacetylase 8 using an in vitro deacetylation assay. In a detailed procedure, 8 μl o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2014
Entry Details
US Patent