BDBM12137 4-(N-(3,4-dichlorophenyl)aminocarbonyl-hydrazinocarbonyl)-benzenesulfonamide::N-{[(3,4-dichlorophenyl)carbamoyl]amino}-4-sulfamoylbenzamide::urea analog 3a

SMILES NS(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)Nc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=FIHDPHXTPMLGSV-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12137   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM12137(4-(N-(3,4-dichlorophenyl)aminocarbonyl-hydrazinoca...)
Affinity DataKi:  7.90nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM12137(4-(N-(3,4-dichlorophenyl)aminocarbonyl-hydrazinoca...)
Affinity DataKi:  13nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita Degli Studi Di Firenze

LigandPNGBDBM12137(4-(N-(3,4-dichlorophenyl)aminocarbonyl-hydrazinoca...)
Affinity DataKi:  1.15E+3nM ΔG°:  -7.96kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed