BDBM12186 (2S)-2-amino-2-phenyl-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)ethan-1-one::isoquinoline derivative 9

SMILES N[C@H](C(=O)N1CCc2ccccc2C1)c1ccccc1

InChI Key InChIKey=MKOHGPTZXZDSJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12186   

TargetDipeptidyl peptidase 8(Human)
National Health Research Institutes

LigandPNGBDBM12186((2S)-2-amino-2-phenyl-1-(1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
National Health Research Institutes

LigandPNGBDBM12186((2S)-2-amino-2-phenyl-1-(1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
National Health Research Institutes

LigandPNGBDBM12186((2S)-2-amino-2-phenyl-1-(1,2,3,4-tetrahydroisoquin...)
Affinity DataIC50: 1.00E+5nMAssay Description:The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2006
Entry Details Article
PubMed