BDBM122705 US8735386, I-175

SMILES CN(C)C1CCN(CCn2ccc(Nc3ncc4CCc5nn(C)c(c5-c4n3)-c3ccccc3)n2)CC1

InChI Key InChIKey=OQTXRWVTVFNVBV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 122705   

TargetInsulin-like growth factor 1 receptor(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM122705(US8735386, I-175)
Affinity DataIC50: 0.400nMpH: 7.4Assay Description:The kinase activity is measured by DELFIA assay (dissociation-enhanced lanthanide fluorescence immunoassay, Perkin Elmer). The cytoplasmic kinase dom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2014
Entry Details
US Patent