BDBM12316 5-[(1E)-(methoxyimino)methyl]-6-(quinolin-6-yloxy)pyrimidin-4-amine::oxime analog 5

SMILES CO\N=C\c1c(N)ncnc1Oc1ccc2ncccc2c1

InChI Key InChIKey=KGYCBUAMHQDXDP-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12316   

TargetVascular endothelial growth factor receptor 2(Rat)
Johnson & Johnson Pharmaceutical

LigandPNGBDBM12316(5-[(1E)-(methoxyimino)methyl]-6-(quinolin-6-yloxy)...)
Affinity DataIC50: 700nMpH: 8.0 T: 2°CAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 5 uM ATP/[gamma-33P]ATP in a streptavidin coated F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2006
Entry Details Article
PubMed