BDBM123348 US8742106, 1.61

SMILES Cn1nc(-c2cccc(F)c2)c2c(cc(OCC(=O)N[C@H]3CCc4ccccc34)nc12)C(F)(F)F

InChI Key InChIKey=FPFXFURKSLMDRG-IBGZPJMESA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123348   

TargetOrexin receptor type 2(Human)
Novartis

US Patent
LigandPNGBDBM123348(US8742106, 1.61)
Affinity DataKd:  89nMpH: 7.5 T: 4°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In DepthDetails US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis

US Patent
LigandPNGBDBM123348(US8742106, 1.61)
Affinity DataKd:  204nMpH: 7.5 T: 4°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In DepthDetails US Patent