BDBM123354 US8742106, 4.1

SMILES C[C@H](NC(=O)COc1cc(C)c2c(nn(C)c2n1)-c1ncccc1F)c1ccc(C)cc1

InChI Key InChIKey=VHPHJZXOLJJSPJ-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 123354   

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis

US Patent
LigandPNGBDBM123354(US8742106, 4.1)
Affinity DataKd:  5nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Novartis

US Patent
LigandPNGBDBM123354(US8742106, 4.1)
Affinity DataKd:  6nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetOrexin receptor type 2(Human)
Novartis

US Patent
LigandPNGBDBM123354(US8742106, 4.1)
Affinity DataKd:  22nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis

US Patent
LigandPNGBDBM123354(US8742106, 4.1)
Affinity DataKd:  27nMpH: 7.5 T: 2°CAssay Description:For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details
US Patent