BDBM123881 US8748418, 26

SMILES CC1(C)OCC(N)=N[C@](C)(c2cc(Nc3cncc(c3)C(F)(F)F)ccc2F)C1(F)F

InChI Key InChIKey=GDPOMHIELXXKQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123881   

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM123881(US8748418, 26)
Affinity DataIC50: 1.90E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM123881(US8748418, 26)
Affinity DataIC50: 3.89E+3nMpH: 4.5Assay Description:The FRET assay was performed essentially as described in Gruninger-Leitch et al., Journal of Biological Chemistry (2002) 277(7) 4687-93 (Substrate an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent