BDBM124171 US8754075, 42

SMILES C[C@]1(F)COC(N)=N[C@]1(C)c1cc(NC(=O)c2ccc(F)cn2)ccc1F

InChI Key InChIKey=NVOQNXJHOVMVBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124171   

TargetBeta-secretase 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM124171(US8754075, 42)
Affinity DataIC50: 11nMT: 2°CAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM124171(US8754075, 42)
Affinity DataIC50: 74nMT: 2°CAssay Description:The assay uses the principle of inhibition of human TMEM27 cleavage by endogenous cellular BACE2 in the Ins1e rat cell line and shedding from the cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent