BDBM124207 US8748458, 15

SMILES ONC(=O)CCCCCCN(c1ccccn1)c1cc(OCc2ccccc2)ccn1

InChI Key InChIKey=HHSNUFVTOCHKST-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 124207   

TargetHistone deacetylase 6(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 3nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 151nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 9(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 423nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent

TargetHistone deacetylase 2(Human)
Karus Therapeutics

US Patent
LigandPNGBDBM124207(US8748458, 15)
Affinity DataIC50: 612nMT: 2°CAssay Description:In vitro HDAC assays were performed using a HDAC fluorescent activity assay kit (Biomol, UK) according to the manufacturer's instructions. Compounds ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2014
Entry Details
US Patent