BDBM124736 US8765940, 4-(6-(3,6-dihydro-2H-pyran-4-yl)-3,3-dimethyl-2,3-dihydro-1H-pyrrolo[3,2-b]pyridin-1-yl)-7-fluoro-3-methyl-2-(2-pyridinyl)quinoline

SMILES Cc1c(nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(cc12)C1=CCOCC1)-c1ccccn1

InChI Key InChIKey=HKXAQMNVSYLNCH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124736   

LigandPNGBDBM124736(US8765940, 4-(6-(3,6-dihydro-2H-pyran-4-yl)-3,3-di...)
Affinity DataKi:  6.47nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent