BDBM124786 US8765940, 1'-(3-methyl-2-phenyl-1,8-naphthyridin-4-yl)-6'-(4-morpholinyl)-1',2,2',3,5,6-hexahydrospiro[pyran-4,3'-pyrrolo[3,2-b]pyridine]

SMILES Cc1c(nc2ncccc2c1N1CC2(CCOCC2)c2ncc(cc12)N1CCOCC1)-c1ccccc1

InChI Key InChIKey=XTDNCMUGAVTARM-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124786   

LigandPNGBDBM124786(US8765940, 1'-(3-methyl-2-phenyl-1,8-naphthyri...)
Affinity DataKi:  4.36nMpH: 7.0Assay Description:A PI3K Alphascreen assay (PerkinElmer, Waltham, Mass.) was used to measure the activity of a panel of four phosphoinositide 3-kinases: PI3Kα, PI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent