BDBM124939 US8765750, Reference Example 12

SMILES Fc1cccc(c1)C(=O)N1CCN(CC1)C(=O)Nc1nc2ccc(Br)cc2s1

InChI Key InChIKey=CFOSRSHKAHRGQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124939   

TargetHematopoietic prostaglandin D synthase(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM124939(US8765750, Reference Example 12)
Affinity DataIC50: 106nMpH: 8.0Assay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2014
Entry Details
US Patent

TargetHematopoietic prostaglandin D synthase(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM124939(US8765750, Reference Example 12)
Affinity DataIC50: 106nMpH: 8.0 T: 2°CAssay Description:The test was carried out according to the method of Urade, Y. et al. (J. Biol. Chem., 262, 3820-3825, (1987)). More specifically, the reaction mixtur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/6/2015
Entry Details
US Patent