BDBM125053 US8772511, 22

SMILES COc1ccc(NC(=O)Nc2ccc3cc(oc3c2)C(=O)N[C@H]2CN3CCC2CC3)cc1

InChI Key InChIKey=DTWUJBKFCQXSLJ-FQEVSTJZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125053   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Bayer Intellectual Property

US Patent
LigandPNGBDBM125053(US8772511, 22)
Affinity DataKi: <1nM ΔG°: <-11.4kcal/molepH: 7.4 T: 2°CAssay Description:Rat brain tissue (hippocampus or whole brain) is homogenized in aqueous homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethy...More data for this Ligand-Target Pair
In DepthDetails US Patent