BDBM125205 US8772495, 2

SMILES CCOc1ccc(cn1)-c1ccc(Cn2c(CC(C)(C)C([O-])=O)c(SC(C)(C)C)c3cc(OCc4ccc(C)cn4)ccc23)cc1

InChI Key InChIKey=DFQGDHBGRSTTHX-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125205   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Panmira Pharmaceuticals

US Patent
LigandPNGBDBM125205(US8772495, 2)
Affinity DataIC50: 2.90nMpH: 7.4Assay Description:Compound 2 was examined for its ability to bind human FLAP using a membrane-binding assay. The affinity of Compound 2 for human FLAP was assessed usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent