BDBM125211 US8772481, 11

SMILES Fc1ccc(Nc2ccc3c(nncc3n2)-c2cccc(c2)C(=O)N2CCOCC2)c(F)c1

InChI Key InChIKey=LEWKZCLPGNEDKS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125211   

TargetMitogen-activated protein kinase 14(Human)
Amgen

US Patent
LigandPNGBDBM125211(US8772481, 11)
Affinity DataIC50: 45nMpH: 7.5Assay Description:Kinase reaction buffer for p38alpha HTRF assays consists of 50 mM Tris-pH 7.5, 5 mM MgCl2, 0.1 mg/mL BSA, 100 uM Na3VO4 and 0.5 mM DTT. HTRF Detectio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2014
Entry Details
US Patent