BDBM125928 6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (3)

SMILES Clc1nc(NCC#C)nc2n(CC#C)cnc12

InChI Key InChIKey=UWENSTZLVADFIJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 125928   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
East China University of Science and Technology

LigandPNGBDBM125928(6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (...)
Affinity DataIC50: 7.57E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
East China University of Science and Technology

LigandPNGBDBM125928(6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
East China University of Science and Technology

LigandPNGBDBM125928(6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
East China University of Science and Technology

LigandPNGBDBM125928(6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
East China University of Science and Technology

LigandPNGBDBM125928(6-Chloro-N,9-di(prop-2-yn-1-yl)-9H-purin-2-amine (...)
Affinity DataIC50: 8.00E+4nMpH: 6.5Assay Description:Enzymatic activity of enzyme was evaluated using pNPP assay. Briefly, a reaction mixture (100 µL) containing 50 mM MOPS (pH 6.5), 2 mM pNPP and recom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2014
Entry Details Article
PubMed