BDBM12639 (2S,5R)-1-(N-(tert-butyl)glycyl)-5-ethynylpyrrolidine-2-carbonitrile::(2S,5R)-1-[2-(tert-butylamino)acetyl]-5-ethynylpyrrolidine-2-carbonitrile::C5-substituted pyrrolidine 32

SMILES CC(C)(C)NCC(=O)N1[C@H](CC[C@H]1C#N)C#C

InChI Key InChIKey=AYFKPVVQCFNFFY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 12639   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM12639((2S,5R)-1-[2-(tert-butylamino)acetyl]-5-ethynylpyr...)
Affinity DataKi:  25nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Abbott Laboratories

LigandPNGBDBM12639((2S,5R)-1-[2-(tert-butylamino)acetyl]-5-ethynylpyr...)
Affinity DataKi: >3.00E+4nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Abbott Laboratories

LigandPNGBDBM12639((2S,5R)-1-[2-(tert-butylamino)acetyl]-5-ethynylpyr...)
Affinity DataKi: >3.00E+4nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed