BDBM12707 6-[2-fluoro-4-(2-methanesulfonylphenyl)phenyl]-1-(4-methoxyphenyl)-5,7-dioxo-1H,4H,5H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carbonitrile::pyrazolo[4,3-d]pyrimidindione 13

SMILES COc1ccc(cc1)-n1nc(C#N)c2[nH]c(=O)n(-c3ccc(cc3F)-c3ccccc3S(C)(=O)=O)c(=O)c12

InChI Key InChIKey=MYCUIGIJETXUNP-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12707   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12707(6-[2-fluoro-4-(2-methanesulfonylphenyl)phenyl]-1-(...)
Affinity DataKi:  3nM ΔG°:  -11.5kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed