BDBM12714 2-{4-[3-(aminomethyl)-1-(4-methoxyphenyl)-7-oxo-1H,6H,7H-pyrazolo[4,3-d]pyrimidin-6-yl]phenyl}benzene-1-sulfonamide::pyrazolo[4,3-d]pyrimidinone 26

SMILES COc1ccc(cc1)-n1nc(CN)c2ncn(-c3ccc(cc3)-c3ccccc3S(N)(=O)=O)c(=O)c12

InChI Key InChIKey=VRIDMBGQPVACOS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12714   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12714(2-{4-[3-(aminomethyl)-1-(4-methoxyphenyl)-7-oxo-1H...)
Affinity DataKi:  22nM ΔG°:  -10.3kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2006
Entry Details Article
PubMed