BDBM12782 5-amidinoindole 16::N-[4-(1H-1,3-benzodiazol-1-yl)phenyl]-2-(5-carbamimidoyl-1H-indol-3-yl)butanamide

SMILES CCC(C(=O)Nc1ccc(cc1)-n1cnc2ccccc12)c1c[nH]c2ccc(cc12)C(N)=N

InChI Key InChIKey=MVIMTQPKTBMOAO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12782   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12782(N-[4-(1H-1,3-benzodiazol-1-yl)phenyl]-2-(5-carbami...)
Affinity DataKi:  2.80nM ΔG°:  -11.5kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12782(N-[4-(1H-1,3-benzodiazol-1-yl)phenyl]-2-(5-carbami...)
Affinity DataKi:  160nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed