BDBM12792 5-amidinoindole 26::N-[4-(1H-1,3-benzodiazol-1-yl)-2-fluorophenyl]-2-(5-carbamimidoyl-1-methyl-1H-indol-3-yl)-3-phenylpropanamide

SMILES Cn1cc(C(Cc2ccccc2)C(=O)Nc2ccc(cc2F)-n2cnc3ccccc23)c2cc(ccc12)C(N)=N

InChI Key InChIKey=CULRMGDBJLVUDS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12792   

TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12792(N-[4-(1H-1,3-benzodiazol-1-yl)-2-fluorophenyl]-2-(...)
Affinity DataKi:  160nM ΔG°:  -9.17kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12792(N-[4-(1H-1,3-benzodiazol-1-yl)-2-fluorophenyl]-2-(...)
Affinity DataKi:  360nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed