BDBM127989 US8796310, 19

SMILES COc1c2CCCC(O)(c3ncc(s3)-c3cc(C)cc(Nc4cc(ccn4)C(F)(F)F)n3)c2ccc1C(O)=O

InChI Key InChIKey=FKOBAHHZUSXBIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127989   

TargetTyrosine-protein kinase SYK(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM127989(US8796310, 19)
Affinity DataIC50: 0.5nMpH: 7.5Assay Description:A recombinant GST-hSyk fusion protein was used to measure potency of compounds to inhibit human Syk activity. The recombinant human GST-Syk (Cama Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2014
Entry Details
US Patent