BDBM12799 4-{[2-(5-carbamimidoyl-1H-indol-3-yl)-3-phenylpropanamido]methyl}-N-(6-methanesulfonyl-1H-1,3-benzodiazol-2-yl)benzamide::5-amidinoindole 33

SMILES CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(CNC(=O)C(Cc4ccccc4)c4c[nH]c5ccc(cc45)C(N)=N)cc3)[nH]c2c1

InChI Key InChIKey=KYRYSUCVLCYOAP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12799   

TargetCoagulation factor IX(Human)
Bristol-Myers Squibb

LigandPNGBDBM12799(4-{[2-(5-carbamimidoyl-1H-indol-3-yl)-3-phenylprop...)
Affinity DataKi:  660nMAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

LigandPNGBDBM12799(4-{[2-(5-carbamimidoyl-1H-indol-3-yl)-3-phenylprop...)
Affinity DataKi:  1.10E+3nM ΔG°:  -8.04kcal/molepH: 7.0 T: 2°CAssay Description:Ki values were obtained from human purified enzyme. All assays were run in microtiter plates. Plates were read for 30 min at 405 nm. Rates were deter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2007
Entry Details Article
PubMed