BDBM128289 US8796295, Table 2: Compound: 13

SMILES Fc1cc(Oc2cncnc2)cc(c1)C(=O)Nc1nc(cs1)C(F)(F)F

InChI Key InChIKey=QFGZDSNEPZPSFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128289   

TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University

US Patent
LigandPNGBDBM128289(US8796295, Table 2: Compound: 13)
Affinity DataIC50: 4.04E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

US Patent
LigandPNGBDBM128289(US8796295, Table 2: Compound: 13)
Affinity DataIC50: 5.12E+3nMAssay Description:The utility of the compounds in accordance with the present invention as negative allosteric modulators of metabotropic glutamate receptor activity, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent