BDBM12838 US8846929, 129

SMILES [H][C@]12CC[C@]([H])(C[C@@]([H])(C1)n1c3ccccc3nc(C(=O)NC(CO)C(O)=O)c1=O)N2C1CCCCCCC1

InChI Key InChIKey=QKTCHVYOFICJPJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12838   

TargetOpioid growth factor receptor-like protein 1(Human)
Purdue Pharma

US Patent
LigandPNGBDBM12838(US8846929, 129)
Affinity DataKi:  13.5nMpH: 7.4Assay Description:Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetKappa-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM12838(US8846929, 129)
Affinity DataKi:  180nMpH: 7.4Assay Description:Radioligand dose displacement assays used 0.4-0.8nM [3H]-U69,593 (NEN; 40 Ci/mmole) with 10-20 ug membrane protein (recombinant kappa opioid receptor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetMu-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM12838(US8846929, 129)
Affinity DataKi:  462nMpH: 7.4Assay Description:Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent

TargetDelta-type opioid receptor(Human)
Purdue Pharma

US Patent
LigandPNGBDBM12838(US8846929, 129)
Affinity DataKi:  2.61E+4nMpH: 7.4Assay Description:Radioligand dose-displacement assays used 0.2nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20ug membrane protein (recombinant delta opioid recepto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2015
Entry Details
US Patent