BDBM128393 US8802695, 9

SMILES CC(C)(O)c1ccc(cc1)C(=O)Nc1cc2n(CC3CC3)ccc2cn1

InChI Key InChIKey=OFLQFDPYHCROCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128393   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM128393(US8802695, 9)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM128393(US8802695, 9)
Affinity DataIC50: 237nMpH: 7.3 T: 2°CAssay Description:The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2015
Entry Details
US Patent