BDBM129007 US8802679, 263

SMILES CN(Cc1cccc(c1)-c1cnc(nc1)N1CCN(CC1)c1ccc(cc1Cl)C(O)=O)C(=O)CN

InChI Key InChIKey=WUPBTBRKQPXTEW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 129007   

TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM129007(US8802679, 263)
Affinity DataIC50: 15nMAssay Description:Inhibition of rat VAP-1 expressed in CHO cells using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed
TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM129007(US8802679, 263)
Affinity DataIC50: 15nMT: 2°CAssay Description:A rat VAP-enzyme 1 (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme suspe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM129007(US8802679, 263)
Affinity DataIC50: 25nMT: 2°CAssay Description:A human VAP-1 enzyme (SSAO) activity was measured by a radiochemistry-enzymatic assay using 14C-benzylamine as an artificial substrate. An enzyme sus...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent

TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM129007(US8802679, 263)
Affinity DataIC50: 25nMAssay Description:Inhibition of human VAP-1 expressed in CHO cells using 14C-benzylamine as substrate preincubated for 20 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2020
Entry Details Article
PubMed