BDBM12934 4-({[4-(Aminosulfonyl)benzoyl]amino}methyl-1-(2,3,4-tri-O-acetyl-beta-D-glucuronic acid methyl ester)-1H-1,2,3-triazole::CHEMBL216563::Glycoconjugate Benzene Sulfonamide 2e::methyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4-{[(4-sulfamoylphenyl)formamido]methyl}-1H-1,2,3-triazol-1-yl)oxane-2-carboxylate

SMILES COC(=O)[C@H]1O[C@H]([C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O)n1cc(CNC(=O)c2ccc(cc2)S(N)(=O)=O)nn1

InChI Key InChIKey=PYTGWGTZAOZYNV-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 12934   

TargetCarbonic anhydrase 2(Human)
Griffith University

LigandPNGBDBM12934(methyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4...)
Affinity DataKi:  7.60nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM12934(methyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4...)
Affinity DataKi:  8.80nMAssay Description:Inhibition of human recombinant CA12 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM12934(methyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4...)
Affinity DataKi:  94nMAssay Description:Inhibition of human recombinant CA14 by CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Griffith University

LigandPNGBDBM12934(methyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4...)
Affinity DataKi:  471nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Griffith University

LigandPNGBDBM12934(methyl (2S,3S,4S,5R,6R)-3,4,5-tris(acetyloxy)-6-(4...)
Affinity DataKi:  5.80E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2007
Entry Details Article
PubMed