BDBM129685 US8802665, 18

SMILES CCOC(=O)N1CCC(CC1)N1CCC1C(=O)N1C[C@@H](C[C@H]1C(=O)NC1(CC1)C#N)Sc1cccc(c1)C(F)(F)F

InChI Key InChIKey=YOOAQZIOEAHGEH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 129685   

TargetCathepsin S(Human)
Genentech

US Patent
LigandPNGBDBM129685(US8802665, 18)
Affinity DataIC50: 8nMpH: 6.5Assay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore wh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2015
Entry Details
US Patent