BDBM130208 US8815881, 170

SMILES COc1ccc(Nc2ccc(F)c(c2)C2(C)N=C(N)N(C)C(=O)C2(C)C)cn1

InChI Key InChIKey=FCFZJECWFCAWSP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 130208   

TargetBeta-secretase 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM130208(US8815881, 170)
Affinity DataIC50: 140nMT: 2°CAssay Description:BACE2 enzyme ectodomain (derived from plasmid pET17b-T7-hu proBACE2) was prepared as described in Ostermann et al., Crystal Structure of Human BACE2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/26/2015
Entry Details
US Patent