BDBM1304 3-Aminopyridin-2(1H)-one analogue 24::5-ethyl-3-[(furan-2-ylmethyl)amino]-6-methyl-1,2-dihydropyridin-2-one::CHEMBL338129

SMILES CCc1cc(NCc2ccco2)c(=O)[nH]c1C

InChI Key InChIKey=ZBEYXZDTUARVJO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 1304   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Organon Research and Development Group

Curated by ChEMBL
LigandPNGBDBM1304(5-ethyl-3-[(furan-2-ylmethyl)amino]-6-methyl-1,2-d...)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of HIV-1 reverse transcriptase (HIV-1 RT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Merck Research Laboratories

LigandPNGBDBM1304(5-ethyl-3-[(furan-2-ylmethyl)amino]-6-methyl-1,2-d...)
Affinity DataIC50: 2.90E+4nMpH: 8.2Assay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2004
Entry Details Article
PubMed