BDBM130505 US8822460, 1::US8822460, 2::US8822460, 3::US8822460, 4::US8822460, 5

SMILES COC1COCCC1NC1CC2OCCC2(C1)C(=O)N1CCc2ncc(cc2C1)C(F)(F)F

InChI Key InChIKey=QOVXPTCADXFNFV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 130505   

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130505(US8822460, 5 | US8822460, 4 | US8822460, 2 | US882...)
Affinity DataIC50: 7nMAssay Description:THP-1 (cells were incubated with 0.5 nM 125I labeled MCP-1 (Perkin-Elmer Life Sciences, Inc. Boston, Mass.) in the presence of varying concentrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130505(US8822460, 5 | US8822460, 4 | US8822460, 2 | US882...)
Affinity DataIC50: 11nMAssay Description:THP-1 (cells were incubated with 0.5 nM 125I labeled MCP-1 (Perkin-Elmer Life Sciences, Inc. Boston, Mass.) in the presence of varying concentrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130505(US8822460, 5 | US8822460, 4 | US8822460, 2 | US882...)
Affinity DataIC50: 16nMAssay Description:THP-1 (cells were incubated with 0.5 nM 125I labeled MCP-1 (Perkin-Elmer Life Sciences, Inc. Boston, Mass.) in the presence of varying concentrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130505(US8822460, 5 | US8822460, 4 | US8822460, 2 | US882...)
Affinity DataIC50: 93nMAssay Description:THP-1 (cells were incubated with 0.5 nM 125I labeled MCP-1 (Perkin-Elmer Life Sciences, Inc. Boston, Mass.) in the presence of varying concentrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM130505(US8822460, 5 | US8822460, 4 | US8822460, 2 | US882...)
Affinity DataIC50: 170nMAssay Description:THP-1 (cells were incubated with 0.5 nM 125I labeled MCP-1 (Perkin-Elmer Life Sciences, Inc. Boston, Mass.) in the presence of varying concentrations...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent