BDBM130919 US8822500, [18]

SMILES CC(Cc1cc(F)ccc1F)Nc1cc[nH]c(=O)c1-c1nc2cc3CN(CCN(C)C)C(=O)c3cc2[nH]1

InChI Key InChIKey=BNPMMVDYMYENIM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 130919   

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Chembridge

US Patent
LigandPNGBDBM130919(US8822500, [18])
Affinity DataIC50: 0.688nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Chembridge

US Patent
LigandPNGBDBM130919(US8822500, [18])
Affinity DataIC50: 4.33nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetSerine/threonine-protein kinase receptor R3(Human)
Chembridge

US Patent
LigandPNGBDBM130919(US8822500, [18])
Affinity DataIC50: 9.16nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

LigandPNGBDBM130919(US8822500, [18])
Affinity DataIC50: 13.1nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent

TargetHepatocyte growth factor receptor(Human)
Chembridge

US Patent
LigandPNGBDBM130919(US8822500, [18])
Affinity DataIC50: 2.00E+3nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
US Patent